| The
Samuel de Champlain Associated International Laboratory
For some fifteen years, the two founder teams have worked closely together, resulting in the publication of more than 100 articles in international periodicals (with a cumulated impact factor of 352 - the articles have been cited more than 2000 times), the co-supervision of PhD theses, bilateral exchange programmes as part of INSERM/FRSQ agreements, joint participation in international congresses, and so on. To further this highly profitable cooperation, the INSERM, the INRS and the University of Rouen have decided to set up the Samuel de Champlain Associated International Laboratory, with a research program focusing on the study of the neuroprotector activities of certain neuropeptides and the development of therapeutic applications, in particular to treat neurodegenerative diseases and cerebral vascular accidents. The Samuel de Champlain Associated International Laboratory is backed by the complementary nature of the French and Canadian teams. The Montreal-based laboratory of Molecular and Pharmacological Studies on Peptides is specialised in the rational design and synthesis of biologically active peptide analogues to increase their stability, selectivity, effectiveness, and/or bioavailability. The Rouen-based laboratory of Cellular and Molecular Neuroendocrinology has developed in vitro, ex vivo and in vivo models used to test the neuroprotector effects of peptide analogues, for the therapeutic treatment of certain pathologies such as the foetal alcoholisation syndrome, neurodegenerative diseases or cerebral vascular accidents. The Associated International
Laboratory has an installed equipment base of a very high level,
integrating in particular the regional cellular imagery research
platform of Haute-Normandie (microsurgery, confocal microscopes,
multiphotonic microscope, video-microscopes, image analysers,
laser microdissection, quantitative PCR etc.) and the proteomic
technical facilities of the IFRMP 23 (2D electrophoresis stations,
digester robots, Proteolab, mass spectrometers, microsequencer
etc.), both of which are RIO-certified. |
