IFRMP 23 : Federate Institute for Multidisciplinary Research on Peptides

Director: Dr. Hubert Vaudry

The Federate Institute for Multidisciplinary Research on Peptides (IFRMP 23), created in 1994 with the first wave of Federate Research Institutes (IFR), is the cornerstone of the chemistry-biology-health research centre of our University.
With its 15 founder teams, including 4 INSERM units (U413, U519, U614 and U644), 1 INSERM AVENIR Team, 4 CNRS units (UMR 6014, UMR 6037, UMR 6522 and FRE 2735,) and 6 UPRES (EA 1780, EA 2656, EA 3222, EA 3233, EA 3234 and EA 3380), IFRMP 23 represents the main research potential in chemistry and biology, federating the work of 350 people including 220 full-time researchers around a seminal theme common too all, that of peptides and proteins with therapeutic applications.
Each time it has been evaluated, the activity of this IFR has been classified A+ and the IFRMP 23 is frequently cited as a model of coordination and efficiency.

Some of the main achievements of the IFRMP 23 worth citing include:

- The creation of a research platform in cellular imagery, designated a regional platform by the Inter-Organisational Assembly (RIO), with one electron microscope, 4 confocal microscopes, 4 video-microscopy workstations, 3 image analysis workstations, 2 phosphorimagers, a laser microdissector, a FlexStation robot and a biomolecule synthesis department;
- The creation of a proteomic engineering platform (approved by the Inter-Organisational Assembly (RIO)) equipped with heavy equipment such as gel analysers, automated digesters, proteome-lab, mass spectrometers, and automatic peptide sequencer;
- The creation of 4 common departments for nucleotidic sequencing, flux cytometry, NMR spectrometry and molecular modelling, and transgenesis;
- Pooling of the technical staff and allocation by the main organisations, specifically to IFRMP 23, of 5 engineers, technicians and administrative staff (ITA) (2 INSERM research engineers (IR), 2 INSERM design engineers (IE), 1 CNRS research technician (TR)) dedicated to the operation of the research platform in cellular imagery and of the various common services;
- The management of common research projects, concretised by a large volume of industrial contracts and by a significant number of articles produced by the cooperation between the various teams of the IFRMP, some of which were published in world-class international periodicals (P.N.A.S., J. Biol. Chem., Circulation, J. Clin. Endocrinol. Metab., Eur. J. Biochem., J. Neurochem., etc.);
- The organisation in June of Scientific workshops of the IFRMP 23, which bring together each year some 250 participants and provides an occasion to invite leading international lecturers. The 11th Scientific workshop of the IFRMP 23 was held on June 10, 2005 at Mont-Saint-Aignan University Hall.
In addition, the IFRMP 23 has strongly supported the emergence of new teams, in particular the AVENIR teams located in U519 (headed by Olivier Boyer) and in the IFRMP 23 (headed by Vincent Laudenbach) and made a major contribution in the creation and development of the INSERM U519, U614 and U644 Units, and UPRES-EA 3222. The Research Master's degree in Cellular Biology and the Norman PhD School in Chemistry-Biology (ED 096) jointly approved by the Universities of Caen and Le Havre, are also largely based on the skills of the IFRMP 23 teams.

Lastly, it is worth recalling that the IFRMP 23 is a leading light in research, with its monthly news bulletins, scientific workshops, seminar cycles, training schools, and international congresses, contributing to the renown of Rouen University.

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